Bruno Donatini graduated in gastroenterology and immunology (1991). He graduated in anti-aging in 2009.

He developed expertise in small gut dysbioses by breath testing, sonography, elastometry and detection of herpes virus DNA.

He investigated the consequences of dysbiosis on vagal nerves or on hyaluronic acid destruction, which may lead to aging, dysimmunity, malignant transformation of stem-cells or neurodegenerative diseases.